 | Augustus turns magic damage into pure damage, which Isaac cannot absorb. For this reason he is often paired with Sebastian - but Seb himself can be countered! |
 | Fluffy prevents his first ult, albeit Isaac will ult again pretty soon. Actually this can be exploited by using Isaac as a bait so that Seb's ult is not the one canceled. This is especially useful against teams with Augustus |
  | Seb and Khorus can prevent his silence |
 | Healers can support the mages until Isaac gets killed since he still suffers a sizeable portion of magic damage taken |
 | Physical attackers can kill him: Isaac is ideally used in a tank position against mages, but he has neither the armor nor the health to tank physical damage |
